TITLE:
Factors Associated with Mortality in Diabetic Patients with End-Stage Renal Failure Starting Emergency Hemodialysis
AUTHORS:
Gaël Honal Mahoungou, Daniel Tony Eyeni Sinomono, Farel Elilié Mawa Ongoth, Éric Ngandzali-Ngabé, Nestor Andzouana, Raissa Laure Mayanda, Aymande Okoumou-Moko, Francky Ambounou, Précieux Ngoma, Berline Ndinga, Héléna Botokoto Bothard, Hardy Ibovi, Richard Loumingou
KEYWORDS:
Diabetic Nephropathy, Emergency Dialysis, Republic of the Congo
JOURNAL NAME:
Open Journal of Nephrology,
Vol.14 No.1,
January
30,
2024
ABSTRACT: Background: Diabetic nephropathy is the leading cause of end-stage chronic kidney disease with poor prognosis in resource-limited settings. This study aimed to determine factors associated with mortality in patients starting dialysis treatment for end-stage chronic renal disease in an emergency context. Patients and Methods: This was a retrospective study from January 2020 to December 2022 at CHU-B. Data from 79 diabetic patients requiring emergency dialysis were compared with those of 79 non-diabetic patients with an end-stage renal disease requiring emergency dialysis. Data were collected from the Nephrology Department registry. We studied their initial clinical and biological profiles and factors related to mortality. Results: Out of 545 compiled records, 79 diabetic chronic kidney disease patients needing dialysis were included (group 1). A control group of 79 non-diabetic chronic kidney disease patients requiring emergency dialysis was also included (group 2). The average age of patients was 53.5 ± 17 years, and the duration of diabetes at dialysis initiation was 14.8 ± 4.3 years. Twenty-three percent were hypertensive. Fifty-two percent of patients experienced intra-dialytic hypotension. Death occurred in 22% of patients. Results show that age (adjusted OR 1.955; CI: 1.025 - 1.086; p-value: Conclusion: Emergency dialysis in diabetics is associated with unfavorable outcomes in terms of mortality. Despite follow-up, renal involvement remains poorly explored, emphasizing the need for physician awareness.