TITLE:
Method Development and Validation of the Simultaneous Analysis of Methylisothiazolinone, Methylchloroisothiazolinone, Benzisothiazolinone and Bronopol in Washing-Up Liquid
AUTHORS:
Etienne Jooken, Ruis Amery, Boudewijn Meesschaert
KEYWORDS:
Preservatives, Analytical Validation, Methylisothiazolinone, Methylchloroisothiazolinone, Benzisothiazolinone, Bronopol, HPLC, Washing-Up Liquid
JOURNAL NAME:
American Journal of Analytical Chemistry,
Vol.15 No.1,
January
30,
2024
ABSTRACT: A method of analysis for the simultaneous determination of methylisothiazolinone (MI), methylchloroisothiazolinone (CMI), benzisothiazolinone (BIT) and Bronopol (BNP) in washing-up liquid was established. The method consisted of a gradient HPLC analysis at three different wavelengths. The four compounds could be analyzed with good precision and accuracy.