TITLE:
The Diagnostic Value of Oligoclonal Band Detection in Viral Encephalitis
AUTHORS:
Anqi Huang, Xianyue Meng, Xueli Li#
KEYWORDS:
Oligoclonal Band Detection, Viral Encephalitis, Routine Analysis of Cerebrospinal Fluid, Age
JOURNAL NAME:
Journal of Behavioral and Brain Science,
Vol.14 No.1,
January
17,
2024
ABSTRACT: Objective: This study aims to explore the differences in cerebrospinal fluid oligoclonal band (CSF-OCB) expression among different age groups in viral encephalitis and its reference value for diagnosis. Methods: Forty-two patients with viral encephalitis were divided into two groups: 25 adults and 17 children. The presence of oligoclonal bands in the cerebrospinal fluid (CSF) was detected using polyacrylamide gel electrophoresis, and CSF routine analysis was conducted for comparative analysis. Results: The CSF-OCB positivity rate was higher in the adult group (48%) compared with the pediatric group (11.76%), with a statistically significant difference (P Conclusion: 1) The expression of CSF-OCB positivity in patients with viral encephalitis is age-related, with higher positivity rates observed in adults compared to children. 2) Although CSF oligoclonal band detection is not a specific diagnostic marker for viral encephalitis in adults, it still holds certain reference value.