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Michetti, L., Maffina, F., Ravasio, R., Barcella, V., Radaelli, M., Chiudinelli, L., Sessa, M. and Alessio, M.G. (2023) Free Light Chains as a Reliable Biomarker of Intrathecal Synthesis in the Diagnosis of CNS Inflammatory Diseases. Journal of Neuroimmunology, 379, 578091.
https://doi.org/10.1016/j.jneuroim.2023.578091

has been cited by the following article:

• TITLE: The Diagnostic Value of Oligoclonal Band Detection in Viral Encephalitis

  AUTHORS: Anqi Huang, Xianyue Meng, Xueli Li^#

  KEYWORDS: Oligoclonal Band Detection, Viral Encephalitis, Routine Analysis of Cerebrospinal Fluid, Age

  JOURNAL NAME: Journal of Behavioral and Brain Science, Vol.14 No.1, January 17, 2024

  ABSTRACT: Objective: This study aims to explore the differences in cerebrospinal fluid oligoclonal band (CSF-OCB) expression among different age groups in viral encephalitis and its reference value for diagnosis. Methods: Forty-two patients with viral encephalitis were divided into two groups: 25 adults and 17 children. The presence of oligoclonal bands in the cerebrospinal fluid (CSF) was detected using polyacrylamide gel electrophoresis, and CSF routine analysis was conducted for comparative analysis. Results: The CSF-OCB positivity rate was higher in the adult group (48%) compared with the pediatric group (11.76%), with a statistically significant difference (P Conclusion: 1) The expression of CSF-OCB positivity in patients with viral encephalitis is age-related, with higher positivity rates observed in adults compared to children. 2) Although CSF oligoclonal band detection is not a specific diagnostic marker for viral encephalitis in adults, it still holds certain reference value.