TITLE:
The Efficacy and Safety of Drug-Coated Balloons in the Treatment of Acute Myocardial Infarction
AUTHORS:
Mingliang Du, Hui Hui
KEYWORDS:
Myocardial Infarction, Drug-Coated Balloon, Drug-Eluting Stents
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.14 No.1,
January
4,
2024
ABSTRACT: The
incidence of acute myocardial infarction (AMI) is increasing year by year,
which seriously endangers human health around the world. The preferred
treatment strategy for AMI patients is the use of drug-eluting stents (DES), as there is ample
evidence to suggest that stent implantation can reduce major adverse
cardiovascular events (MACEs). With
the application of drug-coated balloons (DCBs) and the enhancement of the
concept of interventional without implantation, the question is whether DCBs
can be safely and effectively used in patients with AMI? The purpose of this
study was to investigate the safety and effectiveness of DCBs in the treatment
of AMI. A retrospective review of clinical data was conducted on 55 AMI
patients who underwent primary percutaneous coronary intervention (PCI) from
January 2020 to December 2021. Of these patients, 25 were treated with DCBs and
30 were treated with DESs. Optical coherence tomography (OCT) was used to
measure the minimum lumen diameter, lumen stenosis, and coronary artery
dissection before and after surgery, and angina pectoris attacks and various
MACEs were recorded at 1, 6, and 12 months after surgery. The results showed
that there were no significant differences in clinical baseline data between
the two groups. However, the minimum lumen diameter of the DCB group
immediately after the operation was smaller than that of the DES group, and the
stenosis degree of the lumen in the DCB group was higher than that in the DES
group. The incidence of coronary artery dissection in the DCB group was
significantly higher than that in the DES group, but the majority of them were
type B. At 1, 6, and 12 months after treatment, there was no significant
difference in the occurrence of MACEs between the two groups. In conclusion,
DCBs is a safe and effective treatment for AMI. However, the incidence of
coronary artery dissection in DCB patients is higher than that in DES patients,
but the majority of them are type B.