TITLE:
Advances in Drug Treatment of Fungal Keratitis
AUTHORS:
Xuerong Wu, Jinhua Wang
KEYWORDS:
Fungal Keratitis, Treatment
JOURNAL NAME:
Open Journal of Ophthalmology,
Vol.14 No.1,
December
29,
2023
ABSTRACT: Fungal keratitis is an important cause of corneal blindness in China,
accounting for 45% of infectious keratitis. The main pathogenic
bacteria include yeast, filamentous bacteria and nearly 100 kinds of fungi,
which are difficult to diagnose, difficult to treat and poor prognosis. When
the infected fungal strains have strong virulence and poor drug sensitivity, it
is easy to prolong the disease. Once the fungal infection involves the whole
limbus and reaches the whole layer of the cornea, it will be followed by
intraocular tissue infection such as anterior chamber, lens and vitreous body.
When the infection is difficult to control and the visual function is seriously
damaged, the enucleation of eye contents has to be performed, which causes
irreversible harm to the patient’s
appearance and physical and mental health. Therefore,
in order to gain greater hope for the vision of patients with fungal keratitis,
In recent years, with the continuous progress of clinical medicine and
microbiological diagnostics, the treatment methods of fungal keratitis have
been constantly updated. This article will briefly review the new progress in
drug and surgical treatment of fungal keratitis in recent years to provide
patients with better visual prognosis.