TITLE:
Modeling and Analysis of COVID-19 Optimizated Vaccination Strategies with Age Structure
AUTHORS:
Lu Wang, Linhua Zhou
KEYWORDS:
COVID-19, Dynamical Model, Vaccination Strategy, Strategy Optimization
JOURNAL NAME:
Journal of Applied Mathematics and Physics,
Vol.11 No.12,
December
29,
2023
ABSTRACT: The rational and effective implementation of epidemic prevention and control measures is crucial to controlling the spread of COVID-19, and vaccination is a key part to be considered in the development of epidemic prevention and control strategies. In order to give full play to the greater role of vaccination strategies in epidemic prevention and control, more accurate and efficient vaccination strategies should be explored. Based on the classical SEIR dynamic model, this paper established a COVID-19 dynamic model of population age structure in the form of population grouping and combined with the transmission characteristics of the COVID-19 epidemic. An optimization model with the goal of minimizing daily infection was established to analyze the optimization studies on infection-related specificity of vaccination for different age groups under the condition of limited daily vaccine supply at the early stage of the epidemic, and to obtain the priority of vaccination strategies for Chinese age groups. And the effect of the heterogeneity of infection rate and hospitalization rate on the priority of vaccine allocation.