TITLE:
Ovarian Cancer: Clinical, Therapeutic and Prognostic Aspects at the University Hospital Center of Conakry in Guinea
AUTHORS:
Abdourahamane Diallo, Mamadou Hady Diallo, Fatoumata Bamba Diallo, Ibrahima Koussy Bah, Boubacar Siddy Diallo, Ibrahima Sory Balde, Telly Sy, Namory Keita
KEYWORDS:
Cancer, Ovary, Ignace Deen, Donka
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.13 No.12,
December
29,
2023
ABSTRACT: Background: Ovarian cancer is the seventh most common cancer in women in the world
and is the leading cause of death among gynecological cancers. Objective: The objective of this study was to describe the clinical, therapeutic and
prognostic aspects of ovarian cancer in the both Gynecology-Obstetrics departments Donka
and Ignace Deen of the Conakry University Hospital. Methods: This was a
retrospective, descriptive study lasting 12 years from January 1, 2011 to December 31, 2022, covering the files of patients
treated for ovarian cancer in the both Gynecology-Obstetrics
departments Donka and Ignace Deen. The study focused on the
epidemiological, clinical, histological and therapeutic aspects of the
disease. Results: In total, 135 files of patients with ovarian cancer
were collected out of the 3821 files of gynecological pathologies recorded in
the two departments during the study period, either a frequency of 3.5%. Among
gynecological and breast cancers, ovarian cancer represented 9.1%. The average
age of the patients was 46.3± 17.8 years and the average parity was 4 ± 3. The revealing clinical
signs were dominated by pelvic pain (92.6%) and increased abdominal volume
(53.3%). The diagnosis of the disease was made mainly at stages III and IV
(71.9%). The most common histological type was serous papillary adenocarcinoma
(57.0%). Exclusive surgical treatment was performed in 8.1% of patients,
surgery combined with chemotherapy in 63.0% of patients and exclusive
chemotherapy in 11.1% of patients. After an average follow-up of 42 months, 29
patients out of the 96 operated on were alive (30.2%), 51 had died (53.1%) and
16 patients were lost to follow-up (16.7%). Conclusion: Ovarian cancer
is the third most common cancer in both departments. Diagnosis is often late
and the prognosis is poor.