TITLE:
Investigating the Relationship between TyG, TyG-BMI Index and Laboratory Indicators and COVID-19 Severity
AUTHORS:
Cai Liang, Huaiwu Jiang, Feng Pu, Jing Lin, Weijia Sun, Yun Zhou
KEYWORDS:
COVID-19, TyG Index, TyG-BMI Index, Severity, Liver Function
JOURNAL NAME:
Advances in Infectious Diseases,
Vol.13 No.4,
December
25,
2023
ABSTRACT: Objective: The objective of this study was to investigate the relationship between the triglyceride-glucose (TyG) index, triglyceride-glucose-BMI (TyG-BMI) index, laboratory indices, and disease severity in patients with COVID-19. Methods: A retrospective analysis of COVID-19 patients treated at a tertiary hospital in Mianyang City, Sichuan Province, China, from 1 May to 31 May 2023 was performed. The patients were divided into two groups: 66 cases in the moderate group and 61 cases in the severe group. Additionally, 69 uninfected individuals from the medical examination center during the same period were selected as the control group. Spearman rank correlation was used to determine the correlation between the indices and COVID-19 severity. Multiple logistic regression analysis was performed to identify the factors affecting COVID-19 severity. ROC curves were constructed to assess the predictive value of the TyG and TyG-BMI indices for severe COVID-19. Results: There were significant differences in smoking and diabetes between the three groups (P Conclusion: Smoking, AST, ALB, TyG index, and TyG-BMI index are valuable in assessing the severity of COVID-19, with the TyG-BMI index having a higher predictive value than the TyG index.