TITLE:
Histopathological and Ultrasound Correlation in Women Presenting with Breast Lumps in Yaoundé, Cameroon
AUTHORS:
Yann Chris Mannel Eng, Ambroise Merci Seme Engoumou, Armel Philippe Awana, Sandrine Prisca Ndongo Onembele, Junie Annick Metogo Ntsama, Odile Fernande Zeh
KEYWORDS:
Ultrasound, Histopathological Diagnosis, Breast Lumps, Yaoundé
JOURNAL NAME:
Open Journal of Radiology,
Vol.13 No.4,
December
22,
2023
ABSTRACT: Context: Breast cancer is very deadly among women with higher rates in the developing world. Imaging tools such as ultrasound, can be used to differentiate between the types of breast lumps. This study aimed to determine the value of ultrasound as a first-line examination in the diagnosis of breast masses. Methods: This was a retrospective cross-sectional study of women presenting with breast lumps from November 2022 to June 2023 at the Yaounde General Hospital, which lasted seven months, from November 2022 to June 2023. The sampling was exhaustive and consecutive. Association between variables was studied using the x2 test and concordance between ultrasound and histopathological findings was assessed using the Kappa correlation coefficient. Results: 234 women were included in the study. Their mean age was 46.3 ± 11.4 years. Overall, 15 (6.4%) lumps were benign while 219 (93.6%) were malignant. Triple negative (5.6%) was the most recurrent genomic classification. The correlation between the ultrasound and histopathological findings was significant, with an observed concordance rate at 85.1%, kappa = 0.322 and a p-value Conclusion: The performance of ultrasound in differentiating benign and malignant lesion was high. However, the discordant cases highlight the need for a diagnosis system which blends histopathological and radiological findings for an improved management of patients with breast lumps.