TITLE:
Alobar Holoprosencephaly in a Neonate: A Rare Case Report and Review of the Literature
AUTHORS:
Hanae Bahari, Hanane Hajaj, Anass Ayyad, Sahar Messaoudi, Rim Amrani
KEYWORDS:
Polymalformative Syndrome, Holoprosencephaly, Hydrocephalus
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.13 No.6,
November
28,
2023
ABSTRACT: Holoprosencephaly
(HPE) is a rare brain malformation with multiple etiologies and is often
associated with suggestive facial anomalies. This pathology is the result of a
defect in the early development of the forebrain. There are three clinical
forms: lobar, semi-lobar, alobar and another milder subtype of HPE called
middle interhemispheric. In this clinical case, we present a newborn with
alobar holoprosencephaly and we highlight the clinical, radiological and
progressive clinical aspects of this illness during the neonatal period.