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Lagier, D., Nee, L., Guieu, R., Kerbaul, F., Fenouillet, E., Roux, N., Giorgi, R., et al. (2018) Peri-Operative Oral Caffeine Does Not Prevent Postoperative Atrial Fibrillation after Heart Valve Surgery with Cardiopulmonary Bypass: A Randomised Controlled Clinical Trial. European Journal of Anaesthesiology, 35, 911-918.
https://doi.org/10.1097/EJA.0000000000000824

has been cited by the following article:

• TITLE: Characterizing the Impact of Caffeine on Heart Arrhythmias

  AUTHORS: Siddhant Malani, Gaurav Pathak

  KEYWORDS: Caffeine, Arrhythmias, Atrial Fibrillation

  JOURNAL NAME: Open Journal of Preventive Medicine, Vol.13 No.11, November 23, 2023

  ABSTRACT: Caffeine is one of the most commonly consumed stimulants and is found in many items like coffee and energy drinks. Heart arrhythmias are irregular heart rhythms, which can occur when the electrical signals that control the heart’s rhythm are not functioning properly. Due to the stimulant properties of caffeine, it is theorized that caffeine consumption may cause tachycardias-like ventricular arrhythmias. This review article describes the relationship between caffeine intake and heart arrhythmias using a comprehensive Pub-Med search. A comprehensive search was conducted using the search terms “caffeine arrhythmia” which was conducted and a total of 26 search results were obtained. The majority of clinical studies suggest that there are no strong associations between caffeine consumption and arrhythmias. There is little evidence suggesting a direct relationship between caffeine and ventricular arrhythmias (relative Risk 1.00, 95% CI 0.94 - 1.06; 13.5%, p = 0.32). Conversely, caffeine consumption has an inverse relationship with the risk of atrial fibrillation (p for overall trend = 0.015; p for nonlinearity = 0.27). Caffeine related deaths are uncommon, but certain groups such as infants, psychiatric patients, and athletes may have an increased risk of arrhythmias following caffeine consumption. Overall, caffeine consumption is not strongly linked to heart arrhythmias and limited studies suggest it may reduce the risk of arrhythmias. Although there is not a strong relationship between caffeine intake and heart arrhythmias, it does cause other cardiovascular problems including high blood pressure and hence should be consumed responsibly (40 - 180 mg/day).