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Spellerberg, B. and Brandt, C.M. (2007) Streptococcus. In: Jorgensen, J.H., Carroll, K.C., Funke, G., Pfaller, M.A., Landry, M.L., Richter, S.S. and Warnock, D.W., Eds., Manual of Clinical Microbiology, 9th Edition, Wiley, Hoboken, 412-427.

has been cited by the following article:

• TITLE: Contribution to the Study of Antibiotic Sensitivity of Streptococcus pneumoniae Strains in Spinal Cerebral Fluids in Bangui from 2017 to 2022

  AUTHORS: Zéphirin-Dalengat Vogbia, Ernest Lango Yaya, Marie Colette-Nganda Banguet, Jean de Dieu Longo, Clotaire -Rafaï, Maurel Anicet Adonis Ouoko Fa-Tigbia, Christian Diamant Mossoro, Gérard Gresenguet

  KEYWORDS: Streptococcus pneumoniae, Sensitivity, Antibiotics, Central African Republic

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.16 No.7, July 30, 2023

  ABSTRACT: A prospective and analytical study was carried out from January 2017 to Decem-ber 2022, at the National Laboratory of Clinical Biology and Public Health (LNBCSP) in Bangui. 352 samples of cerebrospinal fluid (CSF) were confirmed out of 2065, coming from the four hospitals in Bangui. This study aimed to evalu-ate the evolution of antibiotic sensitivity to strains of Streptococcus pneumoniae. CSF had been collected from patients who presented with meningeal syndromes. Based on the leukocyte count (White blood cells ≥ 5 mm3), an aliquot was trans-ferred to trans-isolate medium and sent to the LNBCSP for confirmatory testing, culture and determination of antibiotic sensitivity. The antibiotic sensitivity of Streptococcus pneumoniae strains was tested according to the methods recom-mended by the Antibiogram Committee of the French Society of Microbiology. The data collected was entered into Excel 2010 to be analyzed with Epi Info 7.2. Ficher’s exact test, chi2 at the 5% threshold (p