TITLE:
Mitral Valve Abnormalities during Hypertrophic Cardiomyopathy: Study on a Cohort in Dakar
AUTHORS:
Simon Antoine Sarr, Hicham Fassi-Fehri, Marguerite Tening Diouf, Youssou Diouf, Fatou Aw, Joseph Salvador Mingou, Khadimu Rassoul Diop, Serigne Mor Beye, Aliou Alassane Ngaidé, Malick Bodian, Mouhamadou Bamba Ndiaye, Alassane Mbaye, Adama Kane, Maboury Diao, Abdoul Kane
KEYWORDS:
Hypertrophic Cardiomyopathy, Mitral Valve, Obstruction
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.13 No.11,
November
14,
2023
ABSTRACT: INTRODUCTION: Mitral valve abnormalitiesin hypertrophic cardiomyopathy (HCM) are becoming increasingly well defined, and their role in intra-ventricular obstruction is well defined. The aim of this study was to evaluate mitral valve abnormalitiesin patients with HCM. PATIENTS AND METHODS: We conducted a descriptive cross-sectional study from May 1 to July 1, 2022 in the Cardiology Department of Aristide Le Dantec Hospital. All patients with HCM aged at least 18 years old were included. The parameters studied concerned mainly the mitral valvular apparatus (papillary muscles abnormalities, leaflet length, mitral insufficiency). RESULTS: A total of 10 patients were included. Mean age was 58.3. On Doppler echocardiography, mean interventricular septal thickness was 20.6 mm. The mean maximum intra-ventricular gradient was 21.06 mmHg. Two patients had significant intraventricular obstruction. The mean length of the anterior mitral valve leaflet was 28.7 ± 3.55 mm, with extremes of 22 and 33 mm. The posterior mitral leaflet averaged 14.8 ± 3.16 mm. Nine (9) out of 10 patients had an elongated anterior valve leaflet. Elongation of the posterior leaflet was noted in 6 patients. With regard to papillary muscle position, 6 patients had an anterolateral ascending pillary muscle. These patients had a mean intra-ventricular gradient of 25 mmHg, compared with 16.5 mmHg in the others cases. We found no direct insertion on the mitral valve. Mitral insufficiency was noted in 9 patients, including 5 with mild insufficiency and 4 with moderate one. CONCLUSION: Mitral valve abnormalitiesin HCM appear to be frequent. They should be analyzed for a better diagnostic and therapeutic approach.