TITLE:
The Function of Oxytocin in Memory —A General Review of Oxytocin’s Effect on Memory
AUTHORS:
Fan Gao
KEYWORDS:
Oxytocin, Learning and Memory, Long-Term Memory, Short-Term Memory, Emotion
JOURNAL NAME:
World Journal of Neuroscience,
Vol.13 No.4,
November
10,
2023
ABSTRACT: Introduction: While
oxytocin (OT) is widely recognized for its pivotal role in reproductive
behavior and the formation of social bonds, there remains a significant gap in
our understanding of its potential influence on learning and memory processes,
encompassing both social and non-social aspects. Thus this paper serves as an
attempt to investigate the comprehensive role of OT in Physiological, Cognitive,
and Behavioral processes. Method: A comprehensive literature review was
conducted to assemble evidence related to the influence of OT on learning and
memory. Studies encompassing both social and non-social memory were
incorporated into the analysis. Additionally, molecular mechanisms through
which OT could potentially impact neuronal activity in the hippocampus and
amygdala, consequently affecting learning and memory, were also investigated. Results: Our review reveals a spectrum of evidence that both supports and contradicts
the theory that OT plays a significant role in social and non-social memory.
While certain studies suggest a positive impact of OT on memory, others present
findings that argue otherwise. However, multiple potential molecular mechanisms
were discovered that may elucidate OT’s effects on learning and memory,
particularly its potential to modulate
neuronal activity in the hippocampus and amygdala. Conclusion: Despite
the mixed evidence, OT might have a significant role in both social and
non-social memory. Identified molecular mechanisms propose potential ways in
which OT could influence learning and memory. The key role appears to be the
modulation of neuronal activity in the hippocampus and amygdala by OT. Furthermore, it is plausible that OT’s function in
memory is crucial for the social behaviors previously associated with
it. Future research is necessitated to fully unravel the exact mechanisms and
implications of OT’s role in learning and memory.