TITLE:
Biomarkers Associated with Radiation-Induced Lung Injury in Cancer Patients
AUTHORS:
Yuan-Yuan Chen, Dong-Xu Ao, Chen-Yang Zuo, Jun Cai
KEYWORDS:
Radiation Induced Lung Injury, RILI, Fibrosis, Biomarkers
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.11 No.10,
October
27,
2023
ABSTRACT: Radiotherapy (RT) is a common and effective non-surgical treatment for thoracic solid tumors, and radiation-induced lung injury (RILI) is the most common side effect of radiotherapy. Even if RT is effective in the treatment of cancer patients, severe radiation pneumonitis (RP) or pulmonary fibrosis (PF) can reduce the quality of life of patients and may even lead to serious consequences of death. Therefore, how to overcome the problem of accurate prediction and early diagnosis of RT for pulmonary toxicity is very important. This review summarizes the related factors of RILI and the related biomarkers for early prediction of RILI.