TITLE:
Magnusiomyces capitatus in Immune-Competent Patients with Pulmonary Haemorrhage and Systemic Lupus Erythematosus
AUTHORS:
Waleed Amasaib Ahmed, Angham Ahmed Almakki, Abeer Ahmed Bashinim, Abdelgaffar A. Mohamed, Amna Al Kalkami, Mohannad AbuRageila
KEYWORDS:
Magnusiomyces capitatus, Fungal Infection, Bronchoalveolar Lavage, Pulmonary Haemorrhage, SLE (Systemic Lupus Erythematosus), Amphotericin, A Case Report
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.12 No.10,
October
18,
2023
ABSTRACT: Invasive fungal infections have grown significantly over the last two decades, owing to an increase in immunocompromised hosts and geriatric patients. When the host’s defenses are compromised, such infections are associated with severe morbidity and mortality. Here, a rare case of fungal infection in a 61-year-old immunocompetent male patient from Saudi Arabia was reported, who suffered from pulmonary hemorrhage and Systemic Lupus Erythematous. Bronchoalveolar Lavage was used as a diagnostic tool to identify the fungus reported in the case. The pathogenic fungal specie identified as Magnusiomyces capitatus, in macroscopic and microscopic morphological characteristics of the colonies. Based on clinical evidence, liposomal amphotericin formulation was recommended for initial therapy against fungal infection. Also, liposomal amphotericin B induced mycological eradication up to 70 percent in patients with proven Magnusiomyces capitatus infection. In addition to addressing suspected Systemic lupus erythematosus, the patient’s health has improved with no evidence of pulmonary bleeding and hemoptysis.