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Schoenmakers, E., Agostini, M., Mitchell, C., Schoenmakers, N., Papp, L., Rajanayagam, O., Padidela, R., Ceron-Gutierrez, L. and Chatterjee, K. (2010) Mutations in the Selenocysteine Insertion Sequence-Binding Protein 2 Gene Lead to a Multisystem Selenoprotein Deficiency Disorder in Humans. Journal of Clinical Investigation, 120, 4220-4235.
https://doi.org/10.1172/JCI43653

has been cited by the following article:

• TITLE: Evaluation of Glutathione Peroxidase Enzymatic Activity in Seminal Plasma of Patients Treated at the Institute Pasteur in Cote d’Ivoire

  AUTHORS: Marie Florence N’Guessan, Bi Bali Sery, Foua Jonas Vanié Bi, N’Gbesso Amos Ekissi, Youzan Ferdinand Djohan, Founzégué Amadou Coulibaly, Allico Joseph Djaman

  KEYWORDS: Glutathione Peroxidase, Antioxidant, Oligoasthenoteratozoospermia, Azoospermia, Normozoospermia

  JOURNAL NAME: Advances in Reproductive Sciences, Vol.11 No.4, October 18, 2023

  ABSTRACT: Glutathione peroxidase (GPx) is an antioxidant that plays an important role in the maintenance of male fertility. The aim of this study was to compare the profile of enzymatic activity of glutathione peroxidase in the seminal plasma of normozoosperm and those of pathological sperm. Thus, the activity of glutathione peroxidase was determined in the seminal plasma of 20 normozoosperms, 9 azoosperms and 31 oligoasthenoteratozoosperms. It was 37.58 ± 3.14 U/L in normozoosperms, 39.39 ± 2.27 U/L in oligoasthenoteratozoosperms, and 29.77 ± 2.62 U/L in azoosperms. The mean GPx enzyme activity of normozoosperms did not differ significantly from that of oligoasthenoteratozoosperms and azoosperms. In contrast, comparison of enzyme activity between abnormal sperms gave a significant difference. This study showed that glutathione peroxidase enzymatic activity is not related to sperm quality.