TITLE:
Diabetic Nephropathy and Management
AUTHORS:
Pranali M. Wandile
KEYWORDS:
Diabetic Kidney Disease, Diabetic Nephropathy, Chronic Kidney Disease, Cardiovascular Risk Management, Urine Albumin Creatinine Ratio, Renal Replacement Therapy, Chronic Kidney Disease Management
JOURNAL NAME:
Open Journal of Nephrology,
Vol.13 No.3,
September
28,
2023
ABSTRACT: Chronic kidney disease affects people worldwide. Approximately 1 out of 3 adults with diabetes have kidney disease. Among several etiological factors for CKD, diabetes mellitus (DM) and hypertension are the main factors. These factors not only cause CKD but are also responsible for several complications related to CKD. In this article, we have reviewed Diabetic Nephropathy (DN) in terms of etiology, pathophysiology, diagnosis, management, current guidelines for diabetic nephropathy management, and some of the research study findings. Diabetic nephropathy (DN) is the chief factor for end-stage renal disease (ESRD) development across the globe. The primary cause of DN is Diabetes Mellitus, which is an autoimmune lifestyle disorder having several etiological factors. Checking for urine albuminuria, estimated GFR (eGFR), and blood glucose are unswerving tests for DN diagnosis and subsequent monitoring. Controlling hyperglycemia, blood pressure, and proteinuria are critical in stopping the progression of DKD. Clinical practice and evidence-based medicine demonstrated that early diagnosis followed by treatment can prevent or halt DKD progression.