TITLE:
Oral spindle cell lipomas
AUTHORS:
Patrícia C. Caldeira, Vanessa F. Bernardes, Alessandra C. Miranda, Déborah C. Telles, Rodrigo M. R. Batista, Carlos A. Ribeiro, Tarcília A. Silva
KEYWORDS:
Lipoma; Mouth; Soft Tissue Neoplasms
JOURNAL NAME:
Open Journal of Stomatology,
Vol.1 No.4,
December
7,
2011
ABSTRACT: Spindle cell lipoma is an histological type of lipoma which are rarely found in the oral cavity. We describe two cases of intraoral spindle cell lipomas. The pa- tients were men and presented painless slow growing masses in the left cheek and hard palate, measuring 50 × 30 mm and 23 × 20 mm respectively. Microsco- pically, both lesions presented a solid proliferation of mature fat cells intermixed with bundles of connec- tive tissue. Cells were immunopositive for S100 pro- tein and CD34 (one case), with low mitotic activity (Ki-67). The final diagnosis was spindle cell lipomas. The lesions were excised and no recurrence was no- ticed after six months. Oral spindle cell lipomas are unexpected to occur in the oral mucosa, and the main differential diagnosis is well-differentiated liposar- coma/atypical lipoma. Lesions are treated with sur-gical excision and recurrences are rare.