Article citationsMore>>

R. Yamin, E. G. Malgeri, J. A. Sloane, W. T. Mcgraw and C. R. Abraham, “Metalloendopeptidase EC 3.4.24.15 Is Necessary for Alzheimer’s Amyloid-β Peptide Degradation,” Journal of Biological Chemistry, Vol. 274, 1999, pp. 1877-18784.

has been cited by the following article:

• TITLE: The Functions of the Amyloid Precursor Protein Gene and Its Derivative Peptides: III Pharmacological Studies

  AUTHORS: Peter K. Panegyres, Emily R. Atkins

  KEYWORDS: Amyloid Precursor Protein, APP, Genes, Dementia, Alzheimer’s Disease

  JOURNAL NAME: Neuroscience and Medicine, Vol.2 No.4, December 2, 2011

  ABSTRACT: Pharmacological studies reveal APP and Aβ have interactions with glutamate and calcium, cytokines, copper/zinc chelators, secretases and presenilins, nicotinic receptors, acetycholinesterase, neurotrophins, non-steroidal anti-inflame-matory drugs, monoclonal antibodies to Aβ, protease inhibitors, oestrogen, homocysteine, immediate early genes such as c-fos or c-jun and cholesterol. These functional and pharmacological observations highlight the need for greater understanding of APP and Aβ in brain function and have implications for clinical trials.