TITLE:
Metabolic Effect of Dietary Erythritol Intake on Escherichia coli
AUTHORS:
Zhaoyue Zhang
KEYWORDS:
Artificial Sweetener, Erythritol, Hemolytic Activity, Escherichia coli
JOURNAL NAME:
Open Journal of Endocrine and Metabolic Diseases,
Vol.13 No.8,
August
31,
2023
ABSTRACT: Artificial
sweeteners are man-made substitutes for diet that needs low sugars or caloric
intake. Recent studies have shown that AS consumption is possibly associated
with metabolic disturbances and intestinal flora disturbances. Erythritol is a
kind of 4-carbon sugar substitute in the form of sugar alcohol, which may
contribute to the prevention of gingivitis by inhibit the biofilm formation of
oral bacteria. Despite these studies, the data on how erythritol affects
commensal flora causing pathogenicity to remain limited. In this study,
microbiota (Escherichia coli) models were used to investigate the
effects of different concentration of erythritol on the metabolism of bacteria,
especially on Escherichia coli’s growth, transformation efficiency and
hemolytic activity. The results showed that sweeteners decreased the bacteria’s ability to normally grow
in higher concentration, and form biofilms to varying degrees. And the addition
of erythritol in low concentration may have an effect of promote the growth of Escherichia
coli. Habitual
consumption of artificial sweeteners in the diet continues to increase was
associated with the maintenance of micro-ecological equilibrium in gut.