TITLE:
Green Drug Supply Chain Investigation by Time-Market Balance and Risk
AUTHORS:
Mahmoudreza Entezami, Hossein Havaeji
KEYWORDS:
Market Supply Planning, New Product Introduction, Two-Stage Variable Planning, Regulation Affairs
JOURNAL NAME:
World Journal of Engineering and Technology,
Vol.11 No.3,
August
29,
2023
ABSTRACT: The quality of pharmaceutical products plays a crucial role in healthcare
systems such as hospitals for better patient services. Drug Supply Chain Management requires approaches to uncertainty and
risk consideration. This study is a comprehensive multi-objective
mathematical model considering the uncertainties and potential reserves in
supply and medicine. The proposed model includes three
general objective functions that minimize total production costs, including the
costs of transportation, maintenance, breakdown, collection, and disposal of
waste. The model also maximizes the quality of potential storage. The
results show the proposed method has a high quality to solve the model and
leads to the optimization of the results to provide the drug supply chain for
the proposed example. We have identified three important risks and
uncertainties in addressing drug supply planning: the indefinite duration of
the licensing process, the risk of a forced brand change, and indefinite
repayment levels that lead to varied demand diversification. The results of
comparison with other multi-objective optimization methods in existing articles
also show better performance of the proposed model. A significant cost
reduction results from implementing our model instead of using the over-storage
role to estimate the volume of active drug elements, as seen in today’s
industry.