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K. R. Alexander, C. S. Barnes, G. A. Fishman and A. H. Milam, “Nature of the Cone ON-Pathway Dysfunction in Melanoma-Associated Retinopathy,” Investigative Ophthalmology & Visual Science, Vol. 43, No. 4, 2002, pp. 1189-1197.

has been cited by the following article:

• TITLE: Clinical Psychophysical Assessment of the ON- and OFF-Systems of the Magnocellular and Parvocellular Visual Pathways

  AUTHORS: Marcelo Fernandes Costa

  KEYWORDS: Visual Perception, Visual Pathway, Contrast Sensitivity, Psychophysics

  JOURNAL NAME: Neuroscience and Medicine, Vol.2 No.4, December 2, 2011

  ABSTRACT: We developed a psychophysical paradigm for the clinical assessment of the contrast sensitivity (CS) mediated by the ON- and OFF-systems of the Magnocellular and Parvocellular pathways. We designed a stimulus considering two dimensions: two spatial frequencies (0.5 and 4.5 cpd) and two temporal rates of flicker (33 ms and 1500 ms). To evidence the ON- and OFF responses, the CS was measured for two polarities of light with luminance changes of 0.6 dB steps above and below the medium luminance grey background. We tested 38 healthy volunteers. The results shows that Magnocellular contrast sensitivity was higher than Parvocellular for the 33 ms flickering stimulus and the Parvocellular contrast sensitivity was higher than Magnocellular for 1500 ms stimuli. The reliability of the test was checked and confirmed. We concluded that the test performs a rapid measurement of the CS mediated by the ON and OFF systems of Magnocellular and Parvocellular pathways. It is useful in clinical protocols due to its high sensitivity and good reliability.