TITLE:
Association of GA/HbA1c Ratio with Diabetic Retinopathy
AUTHORS:
Tianyao Zhang, Xu Zheng
KEYWORDS:
Type 2 Diabetes, Diabetic Retinopathy, GA/HbA1c Ratio
JOURNAL NAME:
International Journal of Clinical Medicine,
Vol.14 No.8,
August
10,
2023
ABSTRACT: Objectives: The aim of this study was to explore the potential correlation between the GA/HbA1c ratio and diabetic retinopathy (DR) in patients with type 2 diabetes (T2D), as the GA/HbA1c ratio serves as a marker for glycemic variability. Methods: A total of 2565 T2D patients were included in this study and grouped into five categories based on the diagnostic criteria for DR. We examined the impact of the GA/HbA1c ratio on the progression of diabetes. Results: The non-DR group exhibited lower GA/HbA1c levels compared to the DR group. Additionally, as the severity of DR increased among the five groups, there was a corresponding increase in the GA/HbA1c ratio. Logistic regression analysis demonstrated that the GA/HbA1c ratio independently elevated the risk of DR occurrence. Conclusions: The GA/HbA1c ratio can independently predict the occurrence and progression of diabetic retinopathy.