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Halfon, P., Jordana, S., Blachier, S., Cartlamy, P., Kbaier, L., Psomas, C.K., et al. (2023) Anti-Spike Protein to Determine SARS-CoV-2 Antibody Levels: Is There a Specific Threshold Conferring Protection in Immunocompromised Patients? PLOS ONE, 18, e0281257.
https://doi.org/10.1371/journal.pone.0281257

has been cited by the following article:

• TITLE: Waning of Anti-Spike IgG Antibody Titer after COVID-19 Vaccination: Myth or Reality?

  AUTHORS: Laurent Dupoirieux

  KEYWORDS: SARS-CoV-2, COVID-19 Vaccines, Anti-Spike IgG Antibodies

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.11 No.8, August 8, 2023

  ABSTRACT: This observational prospective study was conducted on 25 patients who had received a full 3-dose COVID-19 vaccination scheme with a follow-up ranging from 12 to 19 months after the last injection. The aim of the study was focused on a single biological indicator the anti-spike IgG antibody titer. The age of the patients ranged from 51 to 85 years old. 15 out 25 patients (60%) presented a comorbidity. Our data showed a persistent positive anti-spike IgG antibodies titer ranging from 105 to 5680 BAU/mL (mean: 2661 BAU/mL) in all patients. In view of these results, systematic administration of a SARS-CoV-2 vaccine booster is questionable and should be individually tailored according to the patient medical condition and the anti-spike IgG antibody level.