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Fournier, S., Dauvilliers, Y., Warby, S.C., Labrecque, M., Zadra, A., Boucetta, S., El Gewely, M., Kaddioui, H., Lopez, R., Montplaisir, J.Y., Bareke, E., Tetreault, M. and Desautels, A. (2021) Does Adenosine Deaminase (ADA) Gene Confer Risk of Sleepwalking? Journal of Sleep Research, 31, e13537.

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• TITLE: Somnambulism: Varenicline-Induced Sleep Driving

  AUTHORS: Samer Alkhuja, Monika Girgis, Mohammad Ali, Pravinkumar Patel, Olutunde Odeyemi

  KEYWORDS: Varenicline, Sleep Walking, Arousal Parasomnia

  JOURNAL NAME: Case Reports in Clinical Medicine, Vol.12 No.7, July 7, 2023

  ABSTRACT: Background: Varenicline, which is derived from the cytisine compound, is used to assess in smoking cessation. Sleep driving (SD) is often classified as a variant of somnambulism. Although, somnambulism has been reported as a side effect of varenicline, varenicline-induced sleep driving (VISD) has not been reported. Case Report: A 56-year-old man with a history of 35 pack year smoking who presented for smoking cessation counseling. Treatment with varenicline was initiated. In the following night, the patient drove to a shopping center and woke up in his car. Varenicline was discontinued. SD has not been reported in the following nights. In a repeated attempt to stop smoking, treatment with varenicline was resumed by the patient. SD reoccurred in the following night. Varenicline was discontinued indefinitely, and SD has not been reported.