TITLE:
Correlation between Ultrasound Aspects of Fibrosis and Fibroscan Outcomes of Patients with Chronic Hepatitis B Virus
AUTHORS:
Bénilde Marie-Ange Tiemtore-Kambou, Adjirata Koama, Alice Guingane, Maimouna Payété Gynette Belem, Nina Astrid Ndé Ouedraogo, Madina Napon, Ousséni Diallo, Claudine Lougue, Rabiou Cisse
KEYWORDS:
Fibrosis, HBV, Ultrasound, Fibroscan, Correlation
JOURNAL NAME:
Open Journal of Radiology,
Vol.13 No.2,
June
30,
2023
ABSTRACT: Background: The assessment of liver fibrosis is an essential part of the fol-low-up of patients with chronic HBV. Ultrasound and fibroscan are two com-monly used non-invasive examinations and the purpose of this study is to as-sess the correlation between the results of these two examinations in the as-sessment of liver fibrosis. Methodology: This was a descriptive and analytical cross-sectional study with retrospective collection over a period of 30 months from January 01, 2018 to June 30, 2020 on the correlation between the ultra-sound aspects and the results of the fibroscan of patients with chronic carriers of Hepatitis B virus at the Teaching Hospital of Bogodogo and at the faith-based health center CANDAF. Results: A total of 85 patients with fibrosis were collected. The 30 - 40 age group was the most represented (41.18%), with a male predominance of 52.94%. The patients with a married life were the most represented (77.64%), the social stratum the most represented were the middle managers (32.94%). University level was predominant among educa-tion levels (45.64%). The personal history was traditional circumcision (34.12%), excision (21.18%), manicure (16.47%). The circumstances of the findings were blood donation (34.12%), screening (21.18%), fortuitous findings (16.47%). The association between echostructure and fibrosis on the fibroscan scan was significant (homogeneous hyperechoic echostructure p = 0.0028 and granular echostructure p = 0.0001). Fibrosis on scans had a significant associa-tion with liver contour (Regular contours p = 0.0009 and p = 0.0002). Fibrosis on CT scan had a significant association for the diagnosis of fibrosis on ultra-sound (p = 0.0002 for hepatic steatosis and cirrhosis and p = 0.0013 for hepat-ic dysmorphia), on the other hand, no significant association for hepatomegaly (p = 0.8883). Conclusion: Detecting the presence of fibrosis and monitoring its progression improves the management of patients with chronic liver disease. Ultrasound scans and fibroscan are complementary in the follow-up of pa-tients with chronic HBV.