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Varin, E.M., Mulvihill, E.E., Beaudry, J.L., Pujadas, G., Fuchs, S., Tanti, J.F., Fazio, S., Kaur, K., Cao, X., Baggio, L.L., Matthews, D., Campbell, J.E. and Drucker, D.J. (2019) Circulating Levels of Soluble Dipeptidyl peptidase-4 Are Dissociated from Inflammation and Induced by Enzymatic DPP4 Inhibition. Cell Metabolism, 29, 320-334.E5.
https://doi.org/10.1016/j.cmet.2018.10.001

has been cited by the following article:

• TITLE: Retrospective Assessment of Changes in Perceived Health Status during Continuous Use of a Dietary Supplement

  AUTHORS: Brett J. West, Melissa M. Reid, Fernando A. Swartz, Deanna M. Latson

  KEYWORDS: Dietary Supplement, Health Status, Retrospective Survey

  JOURNAL NAME: Food and Nutrition Sciences, Vol.14 No.6, June 30, 2023

  ABSTRACT: Dietary factors play an important role in human health. Specifically, nutritional interventions may have an impact on the hypothalamic-pituitary axis resulting in positive health outcomes. A retrospective health status survey of 386 respondents was conducted to investigate the potential of a dietary supplement, NutrifiiTM Renew, for improving various health outcomes in comparison to a multivitamin/mineral control group. Among those who ingested Renew, 95% reported experiencing at least some improvement in one or more health categories. Compared to the multivitamin/mineral group, the Renew group reported earlier and/or greater improvements in several health status categories including sleep, reproductive health, memory, energy/stamina, skin and hair quality, flexibility, exercise recovery and feeling rested in the morning. A clear majority (84.9%) of Renew consumers reported experiencing noticeable improvement in some aspect of their health within one month. Among those who felt an improvement in sleep, most reported experiencing a change within one week. These improvements were likely due to the synergistic effects of L-arginine, L-citrulline, L-lysine, and botanical extracts on nitric oxide production, growth hormone (GH) release, and sleep quality. The observed improvements in skin elasticity and hair growth may be related to increased GH levels and IGF-1 production. Overall, these findings suggest that Renew may have potential as a dietary intervention for improving various health outcomes beyond those provided by multivitamin/mineral supplementation alone. Further studies are needed to confirm these findings and elucidate the underlying mechanisms of action.