Article citationsMore>>

Mouridsen, H.T., Langer, S.W., Buter, J., Eidtmann, H., Rosti, G., de Wit, M., et al. (2007) Treatment of Anthracycline Extravasation with Savene (Dexrazoxane): Results from Two Prospective Clinical Multicentre Studies. Annals of Oncology, 18, 546-550. https://doi.org/10.1093/annonc/mdl413

has been cited by the following article:

• TITLE: Effective Treatment of Epirubicin Extravasation with Dexrazoxane: A Case Report of Positive Clinical Outcomes

  AUTHORS: Yassine Sbaiti, Niama Ghozali, Meriem Meliani, Stéphane Ruck, Khadija Darif, Mounia Amzerin, Fatima Zahra El M’rabet

  KEYWORDS: Chemotherapy, Extravasation, Epirubicin, Dexrazoxane

  JOURNAL NAME: Open Access Library Journal, Vol.10 No.6, June 21, 2023

  ABSTRACT: Accidental extravasation of anthracyclines is a rare incident but if ever it happens, it can lead to serious complications, which could go as far as tissue necrosis with the need for surgery in most of the cases. In accordance with current recommendations, intravenous administration of Dexrazoxane within 6 hours of extravasation is recommended to reduce the risk of skin necrosis. We report the case of a 63-year-old patient, diagnosed with breast cancer, who presented with extravasation of Epirubicin, during her first cycle of adjuvant chemotherapy, with a favorable evolution after being treated with Dexrazoxane.