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Aissa, C., Crépin, D., Tetlow, D.J., et al. (2013) Multiple Rhodium-Catalyzed Cleavages of Single C-C Bonds. Organic Letter, 15, 1322-1325.
https://doi.org/10.1021/ol400266g

has been cited by the following article:

• TITLE: Copper-Catalyzed C-C(O)C Bond Cleavage of Monoalkylated β-Diketone: Synthesis of α,β-Unsaturated Ketones

  AUTHORS: Tony Wheellyam Pouambeka, Victor N’goka, Narcisse Nicaise Obaya, Guy Crépin Enoua, Hubert Makomo, Qian Zhan

  KEYWORDS: Monoalkylated β-diketone, α, β-Unsaturated Ketones, Copper-Catalyzed, C-C(O)C Bond Cleavage

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.13 No.2, June 13, 2023

  ABSTRACT: A new and simple route for the synthesis of α,β-unsaturated ketones via cleavage of the C-C(O)C single bond of monoalkylated β-diketone has been described. The reaction was catalyzed by copper, a cheap transition metal in a weakly basic medium (K3PO4) at room temperature. To carry out this study, we first had to synthesize the monoalkylated β-diketones 1. Afterwards, α,β-unsaturated ketones 2 were obtained with high yields around 80%. Finally, all the products were characterized by 1H NMR, 13C NMR, and HRMS spectra.