TITLE:
The Beneficial Effect of 12-Hour Fasting, 45 Minutes Exercise Thrice Weekly and Their Combination on Weight Loss, Anthropometric Measures and Metabolic Syndrome
AUTHORS:
Kamel El-Reshaid, Shaikha Al-Bader, Samah Ghanem
KEYWORDS:
Hyperlipidemia, Hypertension, Metabolic Syndrome, Obesity, Psychiatric Disorders, Type 2 Diabetes, Weight Reduction
JOURNAL NAME:
Food and Nutrition Sciences,
Vol.14 No.5,
May
30,
2023
ABSTRACT: Background: Obesity is the leading preventable cause of death
worldwide. It is associated with significant increases in morbidity and
mortality. Few studies have addressed, prospectively, the impact of life-style
modification in weight-reduction in 1) morbidly obese patients with BMI > 35 kg/m2 and 2) on its associated co-morbid risk factors for metabolic syndrome viz.
high blood pressure, diabetes, hyperlipidemia and steatohepatitis as well as
psychiatric disorders. Patients and Methods: We prospectively evaluated
the role of 1) two meals daily with in between 12-hour fasting, 2) thrice weekly 45-minute active-walk, and 3) their combination, in management of ambulant obese
patients, at BMI of 35 to 39.9 kg/m2 who had such multiple acquired
metabolic disorders. The study was conducted over 3 years with 45 patients in 3
matched groups with regards to gender, age, BMI, waist circumference, lipid profile
(LDL and TG), fibroscan steatosis grade, psychiatric assessment, antidiabetic drugs and antihypertensive
ones. Results: At 6 and 12 months, the 3 regimens were well tolerated and were
effective in weight loss, improvement in
anthropometric measures and management of metabolic syndrome yet the combined
one was significantly better in all endpoints. Conclusion: Our protocols
of exercise and dieting were effective measures in managing obesity and its
associated co-morbidities and their combination is synergetic.