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Gerlier, C., Hoarau, M., Fels, A., Vitaux, H., Mousset, C., Farhat, W., Firmin, M., Pouyet, V., Paoli, A., Chatellier, G. and Ganansia, O. (2021) Differentiating Central from Peripheral Causes of Acute Vertigo in an Emergency Setting with the HINTS, STANDING, and ABCD2 Tests: A Diagnostic Cohort Study. Academic Emergency Medicine, 28, 1368-1378. https://doi.org/10.1111/acem.14337

has been cited by the following article:

• TITLE: Vertigo and H4 Antagonist Effect on Vestibular Symptoms

  AUTHORS: Leena Saeed, Hanna Elbashir Mohamed Ali, Zeinab Abdalgadeer Ali Abdalla, Sarra Fadlalla Elabbas, Marwa Eltaj Eltayeb, Wafa Mukhtar Mohamed Mukhtar

  KEYWORDS: Vertigo, Dizziness, Peripheral Vertigo, Central Vertigo

  JOURNAL NAME: Open Access Library Journal, Vol.10 No.5, May 24, 2023

  ABSTRACT: Vertigo is a condition when a patient feels that the objects around him are moving, and this condition can lead to falls and serious incidences. Vertigo has various etiologies including central, peripheral, psychogenic, and medication-induced vertigo. The most common cause is benign paroxysmal positional vertigo (BPPV) then Meniere’s disease and labyrinthitis should be in the differential diagnosis. Ruling out serious conditions such as stroke is important. Various treatment options are used for vestibular symptoms and vestibular rehabilitation shows a positive result. Management of vertigo is the same for a long time despite the partial effect, unwanted side effects due to some drugs, and the need for multiple medications to relieve the symptoms in some patients. More effective treatment with lesser side effects needs to be used. Recently some in vivo trials come into view that H4 antagonist such as SENS-111 is effective in treating vestibular symptoms. These medications work by blocking the action of histamine, a chemical messenger involved in the immune response. More clinical trials and research need to be done on this type of treatment and other treatment options as this will lead to positive transformation in the future.