TITLE:
Arterial and Venous Thrombosis following Vaccination against COVID-19 with Astra-Zeneca Vaccine Revealing Thrombophilia
AUTHORS:
Bah Mamadou Bassirou, Doumbouya Amadou Dioulde, Balde Mamadou Aliou, Balde Thierno Hamidou, Sylla Ibrahima Sory, Balde Elhadj Yaya, Kone Alpha, Barry Ibrahima Sory, Samoura Sana, Beavogui Mariam, Diakité Souleymane, Balde Mamadou Dadhi
KEYWORDS:
Thrombophilia, Thrombosis, Vaccine, AstraZeneca
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.13 No.4,
April
17,
2023
ABSTRACT: Vaccination against COVID-19 is the most recognised means of containingthe pandemic. Vaccines are not without side effects, particularly vascularthrombosis. But before blaming the vaccines, a thorough assessment of thrombotic risk factors is necessary. We report a case of arterial and venous thrombosis after vaccination with AstraZeneca revealing an exaggeration of factor VIII in a 37-year-old female patient. The angioscanner showed a venous thrombosis of the right subclavian, a pulmonary embolism and the presence of a thrombus in the aorta. The biology was in favour of a high level of factor VIII. The patient was treated with an antivitamin K,andthe clinical evolution was favourable.