TITLE:
A Case of Papillary Thyroid Carcinoma Arising from Struma Ovarii and Extending into the Bladder
AUTHORS:
Vahatra J. Razafimahefa, Zo I. Raivoherivony, Herilalao E. Razafindrafara, Tsitohery F. Andriamampionona
KEYWORDS:
Struma Ovarii, Ovary, Papillary Carcinoma, Thyroid, Bladder Nodule
JOURNAL NAME:
Open Journal of Pathology,
Vol.13 No.2,
April
13,
2023
ABSTRACT: Ovarian goiter is a form of single tissue teratoma of the ovary, accounting for 2% - 3% of mature ovarian teratomas. Malignant transformation may occur in rare cases. Papillary thyroid-type carcinoma represents the most common type of malignant struma ovarii, followed by follicular carcinoma. Malignant struma ovarii is commonly seen in women in the fifth decade. The diagnosis is often made post-operatively after histological examination. Histology also helps assess tumor aggressiveness (mitoses, necrosis, poorly differentiated subtype, etc.). Given the rarity of these lesions, no therapeutic consensus or prognostic value had yet been formally established. We report herein, the case of a 76-year-old woman with a cystic tumor of the right ovary and a nodular lesion of the bladder. The clinical symptomatology is nonspecific, associating abdomino-pelvic pain and a right latero-uterine mass on abdominal palpation. After total hysterectomy with bilateral adnexectomy, the diagnosis of papillary carcinoma arising from struma ovarii and extending into the bladder was made. Through this observation, we suggest to discuss the anatomoclinical particularities of this rare pathological entity.