TITLE:
Therapeutic and Prognostic Aspects of Gynecological and Breast Cancers in Northern Benin from 2010 to 2020
AUTHORS:
Nouéssewa Fanny Maryline Hounkponou, Aurelle Yeyinou Ahouingnan, Roger Klikpezo, Aubin Tchewle, Hubert Laourou, Gaspar Gbessi, Kabibou Salifou
KEYWORDS:
Cancers, Treatment, Prognosis, Benin
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.13 No.2,
February
28,
2023
ABSTRACT: Introduction: Gynaecological and Breast Cancers (GBCs) are a
public health problem and management continues to be a concern. Objective: To study the therapeutic and prognostic aspects of GBC. Method: This was
a cross-sectional and descriptive study from
January 1, 2010, to December 31, 2020. It included cases where the diagnosis of
GBC was made and confirmed on anatomopathological examination and where
treatment was instituted. Male breast cancer cases were excluded. Data were
entered and processed by Epi data 3.1.1. and Epi Info 7.2.0.1. Results: A total of 230 cases of GBC were collected. The mean age was 48.4 ± 11.14 years with extremes of 15 and 80 years. The cancers
were of the breast (55.2%), cervix (28.8%), corpus uteri (7.8%), ovary (5.2%), vulva (1.7%) and vagina (1.3%). Of the 127 breast
cancers, 107 (70.10%) women had undergone total or partial mastectomy
with 89 cases of lymph node dissection (83.20%). Hormone therapy was instituted
in 89 women (71.8%), chemotherapy in 87 women (81.3%), 27 (21.25%) had
undergone immunohistochemistry (IHC). Histopronostic grades were specified in
96 cases, including 12 (12.5%) grade I, 60 (62.5%) grades II and 24 (25%) grade
III. Of the 103 women with gynaecological
cancer, 94.2% had received treatment, which
was specific for 69 women (71.1%). Radiotherapy was not performed in any of the
women. Among the 69 women, 8.7% of deaths were recorded. Conclusion: GBC
is common in northern Benin. Their management is inadequate and mortality
remains high. Priority should be given to prevention.