TITLE:
The Role for AVE0991 (MAS-Receptor Angiotensin II (1-7) Agonist) in Reducing Cisplatin-Induced Acute Kidney Injury on C57BL/6 Mice
AUTHORS:
Chris Mathew
KEYWORDS:
Cisplatin, Acute Kidney Injury, AKI, Cisplatin-Induced Acute Kidney Injury, Nephrotoxicity, Renal Renin Angiotensin System, RAS, AVE0991, MAS-Receptor Angiotensin II (1-7) Agonist
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.11 No.1,
January
31,
2023
ABSTRACT: Acute Kidney Injury (AKI) is a condition that causes nephrotoxicity in kidney tissues due to cisplatin-induced cancer treatments. Hence, it is proposed in this review that AVE0991 (a MAS-receptor Angiotensin II (1-7) agonist) may reduce cisplatin-induced acute kidney injury by promoting nitric oxide production.