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Li, G. D. (2020) Targeting Three-Dimensional Genome Architecture Might Be One of the Mechanisms of Chloroquine’s Diverse Therapeutic Actions. Open Access Library Journal, 7, 1-9. https://doi.org/10.4236/oalib.1106340

has been cited by the following article:

• TITLE: Drug Resistance in Malaria Parasites: Does “Specific Antidrug Substance” Exist?

  AUTHORS: Gao-De Li

  KEYWORDS: Molecular Pharmacology, Drug Resistance in Malaria Parasite, “Specific Antidrug Substance”, 3D Genome Architecture, “Specific Antidrug Group of Protein Combinations”

  JOURNAL NAME: Open Access Library Journal, Vol.10 No.1, January 31, 2023

  ABSTRACT: Development of drug-resistant lines in rodent malaria parasites left us a deep impression on antidrug specificity of antimalarial drug-resistant lines, which is similar to antigen-induced antibody. Based on this comparison, “specific antidrug substance” was proposed to explain antidrug specificity of drug-resistant lines. If “specific antidrug substance” refers to a protein that is quite like antibody, the concept of “specific antidrug substance” is wrong because no such protein has been discovered. However, if “specific antidrug substance” refers to a “specific antidrug group of protein combinations”, the concept of “specific antidrug substance” might be true. A detailed explanation of “specific antidrug substance” is presented in this paper.