TITLE:
Epidemiological and Histopathological Aspects of Chronic Gastritis at the Departmental University Teaching Hospital of Borgou Alibori (CHUD-BA) from 2011 to 2021
AUTHORS:
Luc Valère Codjo Brun, Khadidjatou Sake Alassan, Marie-Claire Assomption Oloufoudi Balle Pognon, Nukunté David Lionel Togbenon, Marie-Noëlle Oréofè Axelle Zomahoun, Raoul Gomez, Moncho Adrien Hodonou, Oumou Boukari, Pacôme Ahouanse, Wilfried Akpo, Falilath Seidou, Marie Thérèse Akele Akpo
KEYWORDS:
Epidemiology, Histopathology, Chronic Gastritis, Dysplasia, Parakou (Benin)
JOURNAL NAME:
Open Journal of Pathology,
Vol.13 No.1,
January
31,
2023
ABSTRACT: Background: Gastritis is better evaluated nowadays since the advent of upper gastrointestinal endoscopy. Despite the availability of this workup in Benin Republic, there is a scarcity of data on chronic gastritis. Objective: This work aimed to study the epidemiological and histopathological aspects of chronic gastritis in the Departmental University Teaching Hospital of Borgou Alibori (CHUD-B/A) from 2011 to 2021. Method: This was a retrospective cross-sectional study with descriptive and analytical purposes, carried out from February 23, 2022 to May 23, 2022, among patients who had undergone gastric biopsy and/or gastrectomy from January 2011 to January 2022 (10 year), and whose specimens were sent into the histopathology section of the CHUD-B/A. Non-probability sampling was performed with exhaustive recruitment. A survey form has been used to collect data from patients’ medical records. Pearson’s chi-square and Fisher’s exact tests have been used as appropriate to determine correlations between variables. Result: A total of 310 cases of chronic gastritis were diagnosed in the histopathology section of the CHUD-B/A from 2011 to 2021. This represented a chronic gastritis frequency of 91.45% for all gastric lesions diagnosed throughout the study period. Erythematous gastropathy was the most frequent (70.35%). Helicobacter pylori was present in 36.77% and dysplasia was observed in 12.26% of cases. Erythematous gastropathy was a predictive factor for the absence of gastric dysplasia in histopathology check up (p-value = 0.042). In contrast, intestinal metaplasia was predictive of the presence of gastric dysplasia in histopathology check up (p-value