TITLE:
Immunologic Thrombocytopenic Purpura Associated with Helicobacter Pylori Infection: A Case Report from Senegal
AUTHORS:
Mohamed Keita, Mouhamed Dieng, Serigne Saliou Mbacké, Ibrahima Thioune, Mouhamadou Sidibé, Baidy Sy Kane
KEYWORDS:
Immunological Thrombocytopenic Purpura, Helicobacter Pylori, Corticosteroids
JOURNAL NAME:
Open Journal of Blood Diseases,
Vol.12 No.4,
November
28,
2022
ABSTRACT: We present a 27-year-old female patient received for epistaxis associated
with gingivorrhagia. In her medical history, she had undergone an oesogastroduodenal fibroscopy one year earlier, which revealed a bulbar ulcer with gastritis. On
admission, she presented with a bleeding syndrome, an anemic syndrome with poor hemodynamic tolerance, and epigastric sensitivity. The blood count
performed in the emergency on the citrate tube showed a bicy-topenia (regenerative anemia + thrombocytopenia).
The HELIKIT test was positive. Thus, the hypothesis of an acute immunological
thrombocytopenic purpura associated with a Helicobacter pylori infection seemed
to us the most probable with a Khellaf hemorrhagic score of 8. She had
benefited from a bolus of methyl prednisone: 15 mg/kg/day for 3 days then relay
per os with prednisone 1 mg/kg/day (and adjuvant treatment); the eradicating
treatment of Helicobacter pylori had been simultaneously started.