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Kassanjee, R., Pilcher, C.D., Busch, M.P., Murphy, G., Facente, S.N., Keating, S.M., Mckinney, E., Marson, K., Price, M.A., Martin, J.N., Little, S.J., Hecht, F.M., Kallas, E.G. and Welte, A. (2016) Viral Load Criteria and Threshold Optimization to Improve HIV Incidence Assay Characteristics. AIDS, 30, 2361-2371.
https://doi.org/10.1097/QAD.0000000000001209

has been cited by the following article:

• TITLE: Impacts of Recent Infection Testing Integration into HIV Surveillance in Ekiti State, South West Nigeria: A Retrospective Cross Sectional Study

  AUTHORS: Daniel Chinenyeike Offie, Leo Akpan, Felix Okoh, Owolagba Femi, Ofuche Eke, Michael Tomori, Abimbola O. Ariyo, Christopher Omisakin

  KEYWORDS: Impacts, Recent Testing, HIV Surveillance

  JOURNAL NAME: World Journal of AIDS, Vol.12 No.4, November 14, 2022

  ABSTRACT: Background: Timely detection of recent HIV infections is critical in achieving the HIV epidemic. The aim of this study was to evaluate the effects of integrating the Recent Infection Testing Algorithm in HIV surveillance in Ekiti State, South West Nigeria. Method: Data from the Nigeria Medical Records System (NMRS)/National Data Repository (NDR) and Index Testing (IT) Services data capturing tools were abstracted for a retrospective cross-sectional study of 719 newly diagnosed HIV-positive cases who were screened for HIV incident infection using Asante rapid recency test kits between August 2020 and June 2022 at 5 selected recency testing health facilities. The venous blood (10 ml) of all the rapid Asante tested recent patients were collected into an EDTA tube and processed for viral load testing. The plasma level of HIV-1 RNA was quantified using the CAP/CTM and cobas 4800 platform at Obafemi Awolowo University Teaching Hospital PCR Laboratory Ife. Chi-square was used to characterize the recency status of the patients. A measure of the association was done using Chi-square, while the p-value of 0.05 was considered statistically significant. Results: The median age of the participants was 39 years. The result from the study showed that of the total number of 719 new cases of diagnosed HIV-positive, 626 of them were screened for rapid Test for Recency infection (RTRI) (87%). Overall, we found that 1.8% (11/626) of clients were classified as recent. The investigation also showed that from the index cases of the 11 confirmed recent infections, a total number of 125 additional positive cases were found. Conclusion: This result indicated a rise in the number of cases discovered in the State. Therefore, incorporating recency testing within regular HIV testing programs becomes essential in order to prioritize clients for index testing and provide useful information on transmission clusters.