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Ingalhalikar, M., Smith, A., Parker, D., Satterthwaite, T.D., Elliott, M.A., Ruparel, K., Hakonarson, H., Gur, R.E., Gur, R.C. and Verma, R. (2014) Sex Differences in the Structural

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• TITLE: Statistical Analysis on Gender Difference in Neural Activity for Spatial Ability Tasks

  AUTHORS: Sung-Ho Kim, Namgil Lee, Chang-Hyun Park

  KEYWORDS: Cross-Correlation, Functional Magnetic Resonance Imaging, Co-Activation and Reverse-Activation, Between and Within Hemisphere

  JOURNAL NAME: Open Journal of Biophysics, Vol.13 No.1, November 10, 2022

  ABSTRACT: Gender differences are investigated from the viewpoint of cognitive neuroscience in the domain of spatial ability. Five task types of geometric problems are used for the collection of task-evoked fMRI data. Although there was no gender-difference in task performance, we found gender differences in neural activity. Some of the important gender differences that we found are 1) that there are far more joint neuro-activations among the brain regions, co-activations or reverse-activations, in males than in females, 2) that the two types of joint activations were nearly half and half in females while it was mostly co-activations in males, 3) that males tend to have more co-activations in the left hemisphere than expected while females tend to have more between-hemisphere co-activations than expected, and 4) that the left-right pairs of BA's are more highly associated than average for males while they are far less associated than average for females.