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Thannickal, T.C., John, J., Shan, L., Swaab, D.F., Wu, M.-F., Ramanathan, L., McGregor, R., et al. (2018) Opiates Increase the Number of Hypocretin-Producing Cells in Human and Mouse Brain and Reverse Cataplexy in a Mouse Model of Narcolepsy. Science Translational Medicine, 10, eaao4953.
https://doi.org/10.1126/scitranslmed.aao4953

has been cited by the following article:

• TITLE: Reduced Cataplexy Symptoms While on Suboxone: A Case Report

  AUTHORS: Nathan B. Omari, Ngugi M. Kinyungu

  KEYWORDS: Narcolepsy, Cataplexy, Suboxone, Sleep, Muscle, Tone

  JOURNAL NAME: Journal of Behavioral and Brain Science, Vol.12 No.11, November 7, 2022

  ABSTRACT: Background: Narcolepsy type 1 is a sleep disorder characterized by excessive sleepiness along with cataplexy and/or hypocretin deficiency. We present a case of narcolepsy type 1 in which the cataplexy symptoms were reduced while on suboxone. Aim: This case report aims to note the reduction of cataplexy symptoms with suboxone. Case Presentation: A 39-year-old female patient with narcolepsy type 1 was referred to our pain clinic for management with suboxone. The patient had tried various other medications for the management of narcolepsy. With opioid management, the patient reported reduced cataplexy symptoms. Conclusion: The case illustrates the scientific thought that opioids could increase hypocretin and reduce symptoms in narcolepsy type 1.