TITLE:
Clinical and Evolutionary Characteristics of Pregnant and Postpartum Women with COVID-19 Admitted to a Hospital in the Central Region of Brazil
AUTHORS:
Eloísa Helena Kubiszeski, Maria Aparecida Mazzutti Verlangieri Do Carmo, Anselmo Verlangieri Do Carmo, Marcial Francis Galera
KEYWORDS:
Analysis of Consequences, Coagulation Disorders, Coronavirus Disease 2019, Intensive Care, Maternal Mortality, Neonatal Outcomes, Pregnancy, SARS-CoV-2
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.12 No.8,
August
18,
2022
ABSTRACT: Objective: This study aims to describe the demographic and
evolutionary characteristics of pregnant and postpartum women
with the novel coronavirus disease (COVID-19) who were admitted to a
medium-sized hospital in Brazil. Methods: This descriptive and
retrospective study collected data from medical records at a hospital in Cuiabá
(MT) from March 2020 to October 2021. Results: Pregnant and postpartum
women with COVID-19 who needed hospitalization
were predominantly mixed-race, from metropolitan areas, and carriers of moderate and severe forms of the
disease. The most prevalent comorbidities in this group were pre-gestational
diabetes, hypertension, asthma, and autoimmune disease, with the primary
risk factors being overweight and obesity. Furthermore, elevated lactate
dehydrogenase (LDH), C-reactive protein (CRP), and D-dimer levels were the
relevant laboratory findings in this group of
patients. The most frequent maternal outcomes were respiratory failure, invasive ventilatory support, thromboembolic phenomena, sepsis, and preterm
labor. Maternal death occurred in 6.4% of pregnant women. Preterm birth and the
need for neonatal intensive care units (NICU) were significant complications in
neonates; stillbirth/neonatal mortality rate is 11.0%. Conclusion: This
study’s findings revealed that the clinical conditions at hospitalization were
associated with worse living conditions and lack of access to healthcare,
resulting in an increased likelihood of severity and deteriorating outcomes in
this group of women and neonates.