TITLE:
Calculous Eosinophilic Cholecystitis in Immunocompetent Patient
AUTHORS:
Mohamed Abughararah, Haytham Alabbas, Saud Almuhammad
KEYWORDS:
Cholecystitis Eosinophilic, Granulomatosis, Polyangiitis, Churg Strauss Syndrome
JOURNAL NAME:
Surgical Science,
Vol.13 No.9,
September
30,
2022
ABSTRACT: We report a case of calculous eosinophilic cholecystitis (EC) without
symptoms suggesting the presence of Eosinophilic Granulomatosis with Polyangiitis (EGPA). A
68 years old male immunocompetent, presented to the Emergency Department (ED),
with a picture of acute calculous cholecystitis. Upon his presentation,
laboratory investigations showed no leukocytosis nor elevation of eosinophils
count in blood serum, however, neutrophils count in serum was found to be high (76%,
normal range up to 70%), then two days later patient underwent laparoscopic
cholecystectomy. His final histopathology showed a picture of Eosinophilic
Cholecystitis, post-operative detailed history, laboratory test including
Antinuclear Antibody (ANA), Antineutrophil cytoplasmic Antibody (ANCA), immunoglobulin,
and chest X-ray ruled out the possibility of the systemic disease (EGPA, Churg
Strauss syndrome), and confirmed that the eosinophilia was localized to the
gallbladder, which caused the picture of acute cholecystitis, and was treated
sufficiently with the laparoscopic cholecystectomy.