TITLE:
Lady Windermere Syndrome: An Interesting Clinical and Radiological Presentation
AUTHORS:
Farid Khan, Wajiha Ali, Muhammad Imtiaz, Uzma Sana Ullah
KEYWORDS:
Lady Windermere Syndrome, Mycobacterium Avium Complex, Dyspnea, Bronchiectasis
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.11 No.9,
September
5,
2022
ABSTRACT: Lady Windermere Syndrome is an uncommon pulmonary disease characteristically observed in elderly white females with chronic cough suppression and dyspnea. It is classically associated with Mycobacterium avium complex (MAC) species. An 84-year-old female was evaluated for longstanding non-productive cough and intermittent dyspnea. A chest computed tomography scan revealed densities in the right upper lobe and scattered nodular-cystic bronchiectasis. Biopsy was negative for malignancy; however, bronchioalveolar lavage studies showed presence of MAC. Patient was treated with a 12-month course of azithromycin, rifampin and ethambutol resulting in resolution of her symptoms.