TITLE:
Urticarial Bullous Pemphigoid: A New Case Report
AUTHORS:
Waqas S. Abdulwahhab, Fatima M. Al Qaydi
KEYWORDS:
Bullous Pemphigoid, Non-Bullous Pemphigoid, Urticarial Bullous Pemphigoid, Direct Immunofluorescence, Doxycycline
JOURNAL NAME:
Journal of Cosmetics, Dermatological Sciences and Applications,
Vol.12 No.3,
September
1,
2022
ABSTRACT: Background: Bullous pemphigoid (BP) is the most common autoimmune bullous disease and it primarily affects the elderly population. It typically presents with tense bullae and severe pruritus. Non-bullous pemphigoid is a subtype of BP characterized by lacking the typical bullae formation with different presentations including erythematous, eczematous, urticarial, polycyclic, targetoid, nodular, lichenoid, vesicular and erythrodermic. Aim: to document a new case presentation of urticarial BP who was treated for several years as chronic urticarial and chronic eczema. Case Report: A 56-year-old male patient presented with a history of recurrent severely pruritic urticarial wheals for 4 years duration involving the lower abdomen, lower back, upper and lower extremities associated with excoriations, keratosis, and post-inflammatory hyperpigmentations on resolved sites, diagnosed as urticarial BP on histopathology & direct immunofluorescence study (DIF) and was improved on systemic doxycycline therapy. Conclusion: BP can be presented with atypical manifestation. Urticarial BP is a rare variant of non-bullous pemphigoid that should be taken into consideration in the differential diagnosis of an atypical urticarial wheal not responding to conventional therapy.