TITLE:
Phytochemical Analysis and Bioactivity Screening of Primary and Secondary Metabolic Products of Medicinal Plants in the Valleys of Medina Region Saudi Arabia
AUTHORS:
Safa Alsaedi, Ghalia Aljeddani
KEYWORDS:
C Phytochemical, Medicinal Plants, GC-MS Analysis, Primary and Secondary Metabolic
JOURNAL NAME:
Advances in Biological Chemistry,
Vol.12 No.4,
August
30,
2022
ABSTRACT: Medicinal plants are highly
valued for their active compounds. These plants can be used in various fields and preservation of these plants in
their environment. The present study aimed to screen medicinal plants used in
traditional medicine in Medina valleys for the presence of metabolites, and to
answer the following question: is the ethnomedicinal importance of medicinal
plants used in Medina valleys conform to their primary and secondary metabolite content. Eight plants (Pulicaria incise, Heliotropium arbainense, Commicarpus grandiflorus, Rumex vesicarius, Senna alexandrina, Rhazya stricta, Withania somnifera and Asphodelus fistulosus) were collected from the Medina valleys and were biochemically analyzed to determine the
different compounds after leaves extraction analyzed statistically to clarify
the content of primary compounds. The
chemical compounds in the most active fraction were determined using
quantitative phytochemical and gas chromatography-mass spectrometry
(GC/MS) analytical methods, comparing the mass spectra of the GC/MS identified
compounds with those of the Center of Excellence in Environmental Studies
(CEES) database library. The result showed 16 aroma compounds representing the
GC/MS analysis revealed the presence of various compounds like 4,4-Dimethyl
octane, 5H-1-Pyrindine and 1,3- Cyclopentadiene,
1,2,5,5-tetramethyl- in the ethanolic extract of Pulicaria incisa. The
most prevalent plants were Pulicaria incisa, Senna alexandrina and Heliotropium arbainense the study plants have high content of protein. There is a need to focus phytochemical screening on
ethnobotanical studies to complete research into traditional medicine
which leads to the discovery of new drugs.