TITLE:
Larynx Cancer: Review of 11 Years of Activity in the ENT and Head and Neck Surgery Department of University Hospital Gabriel Toure, Bamako
AUTHORS:
Diarra Kassim, Konate Nfaly, Sanogo Harouna, Katile Oumar, Dembele Yaya, Soumaoro Siaka, Guindo Boubacary, Cisse Naoma, Coulibaly Kalifa, Kone Fatogoma Issa, Doumbia Kadidiatou, Keita Mohamed Amadou
KEYWORDS:
Laryngeal Cancer, Histology, Treatment, Follow-Up
JOURNAL NAME:
International Journal of Otolaryngology and Head & Neck Surgery,
Vol.11 No.4,
July
28,
2022
ABSTRACT: Objectives: To study the epidemio-clinical, therapeutic and evolutionary aspects of
laryngeal cancers in the ENT department of the University Hospital Gabriel
Toure. Materials and Methods: This was a descriptive, retrospective study over a period of 11 years
from January 2008 to December 2019. We made an exhaustive sampling of all cases
of malignant tumors of the larynx in the ENT department of the University Hospital Gabriel
TOURE. Variables studied: frequency, sex, age, clinic, imaging, histology, TNM
classification, treatment received and follow-up time was 1 to 11 years. Result: we noted a male predominance (44 men/13 women). The average age was 52.23
years, with extremes of 32 and 74 years. Smoking was reported by 40 patients
(72% of cases). The average in pack-years is
29.32 with extremes of 4 to 60 packs/ year.
Alcoholism was reported by 6 patients (9% of cases). Squamous cell carcinoma
was the predominant histological type (100%); extension to 2 or 3 floors was objectified in 69% of cases. Complementary
radiotherapy in 26 patients after total laryngectomy. Chemotherapy was done in
a neoadjuvant situation in 36 cases. Overall survival was: 52.6% at 1 year,
33.3% at 3 years; 26.3% at 5 years and 12.28% at 11 years. Conclusion: Most often, late diagnosis is due to the absence of a national strategy and the
underestimation of the first symptoms. Surgery coupled with radiotherapy is the
treatment of choice.