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Adjanohoun, E.J., Ahyi, A.M., Aké Assi, L., Baniakina, J., Chibon, P., Cusset, G., Doulou, V., Enzanza, A., Eymé, J., Goudoté, E., Keita, A., Mbemba, C., Mollet, J., Moutsamboté, J.M., Mpati, J. and Sita, P. (1988) Traditional Medicine and Pharmacopoeia: Contribution to Ethnobotanical and Floristic Studies in the People’s Republic of Congo. Agency for Cultural and Technical Cooperation, Paris, 606.

has been cited by the following article:

• TITLE: Elucidation of the Probable Ovarian-Dependent Mechanism of the Estrogenic Effects of Buccholzia coriacea and Progesterone Effects of Cogniauxia pololeana in the Rat

  AUTHORS: Bonaventure Max Lazare Peneme, Arnaud Wilfrid Etou Ossibi, Hermann Akassa, Radard Ondélé, Ange Antoine Abena

  KEYWORDS: Castrated Rat, Cogniauxia podolaena, Buchholzia coriacea, Ovary-Dependent

  JOURNAL NAME: Open Journal of Applied Sciences, Vol.12 No.7, July 28, 2022

  ABSTRACT: The present study was carried out with the objective of evaluating, in castrated rats, the utero trophic, hormonal and biochemical activities of aqueous extracts of Buchholzia coriacea (BC) and Cogniauxia podolaena (CP) leaves. Each extract administered at the dose of 600 mg/Kg in castrated rats did not cause a significant change in the fresh weight/dry weight ratio of the uterus compared to castrated rats given distilled water. However, those receiving 17-β-estradiol as a reference product showed a significant (p β estradiol. In addition, the extracts did not cause significant changes in estrogen or progesterone levels in treated rats, as observed with 17-β-estradiol. In addition, the determination of protein and total cholesterol in the uterus of castrated rats treated with each extract did not show significant variation from controls. At the time, castrated rats treated with 17-β-estradiol showed a significant increase (p , these plants would not contain phytohormones.